Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer’s disease

BACKGROUND: Down syndrome (DS), caused by chromosome 21 trisomy, is associated with an ultra-high risk of dementia due to Alzheimer’s disease (AD), driven by amyloid precursor protein (APP) gene triplication. Understanding relevant molecular differences between those with DS, those with sporadic AD...

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Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Startin, Carla M., Ashton, Nicholas J., Hamburg, Sarah, Hithersay, Rosalyn, Wiseman, Frances K., Mok, Kin Y., Hardy, John, Lleó, Alberto, Lovestone, Simon, Parnetti, Lucilla, Zetterberg, Henrik, Hye, Abdul, Strydom, André
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429702/
https://ncbi.nlm.nih.gov/pubmed/30902060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0477-0
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