Development of a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF) for targeted antibody blocking

Targeted antibody blocking enables characterization of binding sites on immunoglobulin G (IgG), and can efficiently eliminate harmful antibodies from organisms. In this report, we present a novel peptide—denoted as a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF)—for targe...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhang, Lin, Shen, Hao, Gong, Yiyi, Pang, Xiaojing, Yi, Meiqi, Guo, Lin, Li, Jin, Arroyo, Sam, Lu, Xin, Ovchinnikov, Sergey, Cheng, Gong, Liu, Xudong, Jiang, Xu, Feng, Shan, Deng, Haiteng
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429600/
https://ncbi.nlm.nih.gov/pubmed/30996912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05273e
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