c-Myc activation promotes cofilin-mediated F-actin cytoskeleton remodeling and telomere homeostasis as a response to oxidant-based DNA damage in medulloblastoma cells

Medulloblastoma (MB) is a common and highly aggressive pediatric brain tumor of a heterogeneous nature. According to transcriptome-based profiling, four molecular subgroups of MB have been revealed, namely WNT, SHH, Group 3 and Group 4. High MYC mRNA expression and MYC gene amplification in MB have...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lewinska, Anna, Klukowska-Rötzler, Jolanta, Deregowska, Anna, Adamczyk-Grochala, Jagoda, Wnuk, Maciej
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429558/
https://ncbi.nlm.nih.gov/pubmed/30901604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101163
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