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Extracellular Spermine Activates DNA Methyltransferase 3A and 3B
We first demonstrated that long-term increased polyamine (spermine, spermidine, putrescine) intake elevated blood spermine levels in mice and humans, and lifelong consumption of polyamine-rich chow inhibited aging-associated increase in aberrant DNA methylation, inhibited aging-associated pathologic...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6429523/ https://ncbi.nlm.nih.gov/pubmed/30871110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051254 |
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