Multiple Targets of 3-Dehydroxyceanothetric Acid 2-Methyl Ester to Protect Against Cisplatin-Induced Cytotoxicity in Kidney Epithelial LLC-PK1 Cells

Chronic exposure to cisplatin, a potent anticancer drug, causes irreversible kidney damage. In this study, we investigated the protective effect and mechanism of nine lupane- and ceanothane-type triterpenoids isolated from jujube (Ziziphus jujuba Mill., Rhamnaceae) on cisplatin-induced damage to kid...

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Publicat a:Molecules
Autors principals: Lee, Dahae, Kim, Ki Hyun, Lee, Won Yung, Kim, Chang-Eop, Sung, Sang Hyun, Kang, Kyo Bin, Kang, Ki Sung
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429383/
https://ncbi.nlm.nih.gov/pubmed/30832267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050878
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