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Bee Venom and Its Peptide Component Melittin Suppress Growth and Migration of Melanoma Cells via Inhibition of PI3K/AKT/mTOR and MAPK Pathways

Malignant melanoma is the deadliest form of skin cancer and highly chemoresistant. Melittin, an amphiphilic peptide containing 26 amino acid residues, is the major active ingredient from bee venom (BV). Although melittin is known to have several biological activities such as anti-inflammatory, antib...

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Pubblicato in:Molecules
Autori principali: Lim, Haet Nim, Baek, Seung Bae, Jung, Hye Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429308/
https://ncbi.nlm.nih.gov/pubmed/30866426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050929
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