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Regulatory Effect of DNA Topoisomerase I on T3SS Activity, Antibiotic Susceptibility and Quorum- Sensing-Independent Pyocyanin Synthesis in Pseudomonas aeruginosa

Topoisomerases are required for alleviating supercoiling of DNA during transcription and replication. Recent evidence suggests that supercoiling of bacterial DNA can affect bacterial pathogenicity. To understand the potential regulatory role of a topoisomerase I (TopA) in Pseudomonas aeruginosa, we...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yan, Rong, Hu, Shikun, Ma, Ning, Song, Peiqing, Liang, Qingqing, Zhang, Huiqun, Li, Yanqi, Shen, Lixin, Duan, Kangmin, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429228/
https://ncbi.nlm.nih.gov/pubmed/30841529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051116
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