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First Total Synthesis of Varioxiranol A

The paper describes the first total synthesis of natural varioxiranol A by chiral pool approach and confirmation of its absolute configuration by single-crystal X-ray analysis. The target varioxiranol A and its 4-epimer were obtained after 10 steps from single and available chiral source 1,2-O-isopr...

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Foilsithe in:Molecules
Main Authors: Lásiková, Angelika, Doháňošová, Jana, Štiblariková, Mária, Parák, Martin, Moncol, Ján, Gracza, Tibor
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429112/
https://ncbi.nlm.nih.gov/pubmed/30823483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050862
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