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HER2 Directed Antibody-Drug-Conjugates beyond T-DM1 in Breast Cancer

Since the discovery of the human epidermal growth factor receptor 2 (HER2) as an oncogenic driver in a subset of breast cancers and the development of HER2 directed therapies, the prognosis of HER2 amplified breast cancers has improved meaningfully. Next to monoclonal anti-HER2 antibodies and tyrosi...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Rinnerthaler, Gabriel, Gampenrieder, Simon Peter, Greil, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429068/
https://ncbi.nlm.nih.gov/pubmed/30841523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20051115
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