Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia

Acute myeloid leukemia (AML) with mutated nucleophosmin (NPM1) has been defined as a distinct leukemia entity in the 2016 updated WHO classification of myeloid neoplasm. Our previous report showed that autophagic activity was elevated in NPM1-mutated AML, but the underlying molecular mechanisms rema...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Biol Sci
Egile Nagusiak: Wang, Lu, Yang, Liyuan, Yang, Zailin, Tang, Yuting, Tao, Yao, Zhan, Qian, Lei, Li, Jing, Yipei, Jiang, Xueke, Jin, Hongjun, Zou, Qin, Xian, Jingrong, Zhang, Ling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ivyspring International Publisher 2019
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429014/
https://ncbi.nlm.nih.gov/pubmed/30906218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.30290
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak