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Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

Macroautophagy is an evolutionarily conserved cellular maintenance program, meant to protect the brain from premature aging and neurodegeneration. How neuronal autophagy, usually loosing efficacy with age, intersects with neuronal processes mediating brain maintenance remains to be explored. Here, w...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bhukel, Anuradha, Beuschel, Christine Brigitte, Maglione, Marta, Lehmann, Martin, Juhász, Gabor, Madeo, Frank, Sigrist, Stephan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428838/
https://ncbi.nlm.nih.gov/pubmed/30899013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09262-2
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