AIM2 Inflammasome Activation Leads to IL-1α and TGF-β Release From Exacerbated Chronic Obstructive Pulmonary Disease-Derived Peripheral Blood Mononuclear Cells

Chronic obstructive pulmonary disease (COPD) is now the fourth-leading cause of death worldwide and its prevalence is increasing. The progressive decline of lung function and airway remodelling are a consequence of chronic inflammatory responses. It was recently postulated the involvement of the inf...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Colarusso, Chiara, Terlizzi, Michela, Molino, Antonio, Imitazione, Pasquale, Somma, Pasquale, Rega, Roberto, Saccomanno, Antonello, Aquino, Rita P., Pinto, Aldo, Sorrentino, Rosalinda
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428726/
https://ncbi.nlm.nih.gov/pubmed/30930781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00257
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