A Synthetic Nanoparticle Based Vaccine Approach Targeting MSP4/5 Is Immunogenic and Induces Moderate Protection Against Murine Blood-Stage Malaria

Malaria remains a significant health problem in many tropical and sub-tropical regions. The development of vaccines against the clinically active blood-stage of infection needs to consider variability and polymorphism in target antigens, and an adjuvant system able to induce broad spectrum immunity...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wilson, Kirsty L., Pouniotis, Dodie, Hanley, Jennifer, Xiang, Sue D., Ma, Charles, Coppel, Ross L., Plebanski, Magdalena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428706/
https://ncbi.nlm.nih.gov/pubmed/30930890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00331
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