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Protein-nucleic acid interactions of LINE-1 ORF1p
Long interspersed nuclear element 1 (LINE-1 or L1) is the dominant retrotransposon in mammalian genomes. L1 encodes two proteins ORF1p and ORF2p that are required for retrotransposition. ORF2p functions as the replicase. ORF1p is a coiled coil-mediated trimeric, high affinity RNA binding protein tha...
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| Published in: | Semin Cell Dev Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6428221/ https://ncbi.nlm.nih.gov/pubmed/29596909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2018.03.019 |
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