Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania

BACKGROUND: The World Health Organization recommends regular therapeutic efficacy studies (TES) to monitor the performance of first and second-line anti-malarials. In 2016, efficacy and safety of artemether-lumefantrine (AL) for the treatment of uncomplicated falciparum malaria were assessed through...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Ishengoma, Deus S., Mandara, Celine I., Francis, Filbert, Talundzic, Eldin, Lucchi, Naomi W., Ngasala, Billy, Kabanywanyi, Abdunoor M., Mahende, Muhidin K., Kamugisha, Erasmus, Kavishe, Reginald A., Muro, Florida, Mohamed, Ally, Mandike, Renata, Mkude, Sigsbert, Chacky, Frank, Paxton, Lynn, Greer, George, Kitojo, Chonge A., Njau, Ritha, Martin, Troy, Venkatesan, Meera, Warsame, Marian, Halsey, Eric S., Udhayakumar, Venkatachalam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427902/
https://ncbi.nlm.nih.gov/pubmed/30898164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2730-1
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