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Effect of Lactamase Inhibitors on the Biosensor Penp during the Measurement of Lactam Antibiotics Concentration

PenP is a fluorescent biosensor of lactam antibiotics (LA). It is structurally derived from the mutant lactamase TEM-1 comprising the substitution E166C, where fluorescein is covalently linked to cysteine. The presence of LA in the medium produces a change in the intrinsic fluorescence level of the...

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Detalhes bibliográficos
Publicado no:Sensors (Basel)
Main Authors: Soto, Dagoberto, Silva, Camila, Ugalde, Cristian, Wong, Kwok-Yin, Leung, Yun-Chung, So, Lok-Yan, Andresen, Max
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6427286/
https://ncbi.nlm.nih.gov/pubmed/30870966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s19051237
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