Quantification of Tyrosine Hydroxylase and ErbB4 in the Locus Coeruleus of Mood Disorder Patients Using a Multispectral Method to Prevent Interference with Immunocytochemical Signals by Neuromelanin

The locus coeruleus (LC) has been studied in major depressive disorder (MDD) and bipolar disorder (BD). A major problem of immunocytochemical studies in the human LC is interference with the staining of the immunocytochemical end-product by the omnipresent natural brown pigment neuromelanin. Here, w...

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Veröffentlicht in:Neurosci Bull
Hauptverfasser: Guo, Lei, Stormmesand, Jochem, Fang, Zheng, Zhu, Qingbin, Balesar, Rawien, van Heerikhuize, Joop, Sluiter, Arja, Swaab, Dick, Bao, Ai-Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426904/
https://ncbi.nlm.nih.gov/pubmed/30706412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-019-00339-y
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