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Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling

Development of lymphatics takes place during embryogenesis, wound healing, inflammation, and cancer. We previously showed that Wnt5a is an essential regulator of lymphatic development in the dermis of mice, however, the mechanisms of action remained unclear. Here, whole-mount immunostaining shows th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lutze, Grit, Haarmann, Anna, Demanou Toukam, Jules A., Buttler, Kerstin, Wilting, Jörg, Becker, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426866/
https://ncbi.nlm.nih.gov/pubmed/30894622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41299-7
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