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Werner Helicase Control of Human Papillomavirus 16 E1-E2 DNA Replication Is Regulated by SIRT1 Deacetylation

Human papillomaviruses (HPV) are double-stranded DNA viruses causative in a host of human diseases, including several cancers. Following infection, two viral proteins, E1 and E2, activate viral replication in association with cellular factors and stimulate the DNA damage response (DDR) during the re...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Das, Dipon, Bristol, Molly L., Smith, Nathan W., James, Claire D., Wang, Xu, Pichierri, Pietro, Morgan, Iain M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426601/
https://ncbi.nlm.nih.gov/pubmed/30890607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00263-19
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