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Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines

Mucosal and skin tissues form barriers to infection by most bacterial pathogens. Staphylococcus aureus causes diseases across these barriers in part dependent on the proinflammatory properties of superantigens. We showed, through use of a CRISPR-Cas9 CD40 knockout, that the superantigens toxic shock...

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Bibliografiset tiedot
Julkaisussa:mBio
Päätekijät: Schlievert, Patrick M., Cahill, Michael P., Hostager, Bruce S., Brosnahan, Amanda J., Klingelhutz, Aloysius J., Gourronc, Francoise A., Bishop, Gail A., Leung, Donald Y. M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426597/
https://ncbi.nlm.nih.gov/pubmed/30890614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00214-19
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