OptRAM: In-silico strain design via integrative regulatory-metabolic network modeling

The ultimate goal of metabolic engineering is to produce desired compounds on an industrial scale in a cost effective manner. To address challenges in metabolic engineering, computational strain optimization algorithms based on genome-scale metabolic models have increasingly been used to aid in over...

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Опубликовано в: :PLoS Comput Biol
Главные авторы: Shen, Fangzhou, Sun, Renliang, Yao, Jie, Li, Jian, Liu, Qian, Price, Nathan D., Liu, Chenguang, Wang, Zhuo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426274/
https://ncbi.nlm.nih.gov/pubmed/30849073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006835
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