Cell Penetration, Herbicidal Activity, and in-vivo-Toxicity of Oligo-Arginine Derivatives and of Novel Guanidinium-Rich Compounds Derived from the Biopolymer Cyanophycin

Oligo-arginines are thoroughly studied cell-penetrating peptides (CPPs, Figures 1 and 2). Previous in-vitro investigations with the octaarginine salt of the phosphonate fosmidomycin (herbicide and anti-malaria drug) have shown a 40-fold parasitaemia inhibition with P. falciparum, compared to fosmido...

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Vydáno v:Helv Chim Acta
Hlavní autoři: Grogg, Marcel, Hilvert, Donald, Ebert, Marc-Olivier, Beck, Albert K., Seebach, Dieter, Kurth, Felix, Dittrich, Petra S., Sparr, Christof, Wittlin, Sergio, Rottmann, Matthias, Mäser, Pascal
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426238/
https://ncbi.nlm.nih.gov/pubmed/30905972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hlca.201800112
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