Adapting Clinical Trial Design to Maintain Meaningful Outcomes during a Multicenter Asthma Trial in the Precision Medicine Era

Precision medicine is expected to impact the care of people with asthma, given its high disease prevalence, heterogeneity of pathophysiologic mechanisms, and consequent clinical phenotypes. A novel phenotype-stratified clinical trial conducted by the NHLBI AsthmaNet Consortium, titled Steroids in Eo...

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Vydáno v:Contemp Clin Trials
Hlavní autoři: Sorkness, Christine A., King, Tonya S., Dyer, Anne-Marie, Chinchilli, Vernon M., Mauger, David T., Krishnan, Jerry A., Blake, Kathryn, Castro, Mario, Covar, Ronina, Israel, Elliot, Kraft, Monica, Lang, Jason E., Lugogo, Njira, Peters, Stephen P., Wechsler, Michael E., Wenzel, Sally E., Lazarus, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425934/
https://ncbi.nlm.nih.gov/pubmed/30593883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2018.12.012
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