Immune Cell Infiltration of the Primary Tumor, Not PD-L1 Status, Is Associated With Improved Response to Checkpoint Inhibition in Metastatic Melanoma

Immune checkpoint inhibition has resulted in dramatic improvements in overall and relapse-free survival in patients with metastatic melanoma. The most commonly used immune checkpoint inhibitors are monoclonal antibodies targeting programmed cell death protein 1 and cytotoxic T-lymphocyte-associated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Med (Lausanne)
Prif Awduron: Kümpers, Christiane, Jokic, Mladen, Haase, Ozan, Offermann, Anne, Vogel, Wenzel, Grätz, Victoria, Langan, Ewan A., Perner, Sven, Terheyden, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019
Pynciau:
Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425878/
https://ncbi.nlm.nih.gov/pubmed/30931305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00027
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