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Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma

BACKGROUND: Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated. The main harmful component of LPR is pepsin, which has been shown to induce mucosal inflammation by...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Tan, Jia-Jie, Wang, Lu, Mo, Ting-Ting, Wang, Jie, Wang, Mei-Gui, Li, Xiang-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425698/
https://ncbi.nlm.nih.gov/pubmed/30936780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0772-7
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