Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors

BACKGROUND: Molecularly targeted therapies using receptor inhibitors, small molecules or monoclonal antibodies are routinely applied in oncology. Verification of target expression should be mandatory prior to initiation of therapy, yet, determining the expression status is most challenging in recurr...

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發表在:J Transl Med
Main Authors: Schäfer, Niklas, Gielen, Gerrit H., Rauschenbach, Laurèl, Kebir, Sied, Till, Andreas, Reinartz, Roman, Simon, Matthias, Niehusmann, Pitt, Kleinschnitz, Christoph, Herrlinger, Ulrich, Pietsch, Torsten, Scheffler, Björn, Glas, Martin
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425567/
https://ncbi.nlm.nih.gov/pubmed/30894200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1846-y
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