Calcium Signaling and Contractility in Cardiac Myocyte of Wolframin Deficient Rats

Wolframin (Wfs1) is a membrane protein of the sarco/endoplasmic reticulum. Wfs1 mutations are responsible for the Wolfram syndrome, characterized by diabetic and neurological symptoms. Although Wfs1 is expressed in cardiac muscle, its role in this tissue is not clear. We have characterized the effec...

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Publicado en:Front Physiol
Autores principales: Cagalinec, Michal, Zahradníková, Alexandra, Kováčová, Dominika, Paulis, Ludovit, Kureková, Simona, Hot’ka, Matej, Pavelková, Jana, Plaas, Mario, Novotová, Marta, Zahradník, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425137/
https://ncbi.nlm.nih.gov/pubmed/30930784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00172
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