Calcium Signaling and Contractility in Cardiac Myocyte of Wolframin Deficient Rats

Wolframin (Wfs1) is a membrane protein of the sarco/endoplasmic reticulum. Wfs1 mutations are responsible for the Wolfram syndrome, characterized by diabetic and neurological symptoms. Although Wfs1 is expressed in cardiac muscle, its role in this tissue is not clear. We have characterized the effec...

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Опубликовано в: :Front Physiol
Главные авторы: Cagalinec, Michal, Zahradníková, Alexandra, Kováčová, Dominika, Paulis, Ludovit, Kureková, Simona, Hot’ka, Matej, Pavelková, Jana, Plaas, Mario, Novotová, Marta, Zahradník, Ivan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Physiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425137/
https://ncbi.nlm.nih.gov/pubmed/30930784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00172
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