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Impaired copper transport in schizophrenia results in a copper-deficient brain state: a new side to the dysbindin story.

Several schizophrenia brain regions exhibit decreased dysbindin. Dysbindin modulates copper transport crucial for myelination, monoamine metabolism, and cellular homeostasis. Schizophrenia patients (SZP) exhibit increased plasma copper, while copper-decreasing agents produce schizophrenia-like behav...

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Bibliographic Details
Published in:World J Biol Psychiatry
Main Authors: Schoonover, Kirsten E., Queern, Stacy L., Lapi, Suzanne E., Roberts, Rosalinda C.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424639/
https://ncbi.nlm.nih.gov/pubmed/30230404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15622975.2018.1523562
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