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Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids

Host-gut microbiota metabolic interactions are closely associated with health and disease. A manifestation of such co-metabolism is the vast structural diversity of bile acids (BAs) involving both oxidative stereochemistry and conjugation. Herein, we describe the development and validation of a LC-M...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Zhu, Pingping, Zhang, Jian, Chen, Yujie, Yin, Shanshan, Su, Mingming, Xie, Guoxiang, Brouwer, Kim L.R., Liu, Changxiao, Lan, Ke, Jia, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424582/
https://ncbi.nlm.nih.gov/pubmed/29907951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-1183-7
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