Increased Bioavailability of Cyclic Guanylate Monophosphate Prevents Retinal Ganglion Cell Degeneration

The nitric oxide – guanylyl cyclase-1 – cyclic guanylate monophosphate (NO-GC-1–cGMP) pathway has emerged as a potential pathogenic mechanism for glaucoma, a common intraocular pressure (IOP)-related optic neuropathy characterized by the degeneration of retinal ganglion cells (RGCs) and their axons...

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Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Wareham, Lauren K., Dordea, Ana C., Schleifer, Grigorij, Yao, Vincent, Batten, Annabelle, Fei, Fei, Mertz, Joseph, Gregory-Ksander, Meredith, Pasquale, Louis R., Sappington, Rebecca M., Buys, Emmanuel S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424569/
https://ncbi.nlm.nih.gov/pubmed/30213732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.09.002
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