Cytomegalovirus-specific CD8+ T-cells are associated with a reduced incidence of early relapse after allogeneic stem cell transplantation

Leukemia relapse is the main cause for mortality after allogeneic stem cell transplantation (allo-SCT). Donor-derived allo-immune responses eliminate the residual host hematopoiesis and protect against relapse. Cytomegalovirus (CMV) reactivation (CMV-R) after allo-SCT may trigger anti-leukemic effec...

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Опубликовано в: :PLoS One
Главные авторы: Varanasi, Pavankumar Reddy, Ogonek, Justyna, Luther, Susanne, Dammann, Elke, Stadler, Michael, Ganser, Arnold, Borchers, Sylvia, Hambach, Lothar, Weissinger, Eva M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424430/
https://ncbi.nlm.nih.gov/pubmed/30889204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213739
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