Dipeptidyl dipeptidase-4 inhibitor recovered ischemia through an increase in vasculogenic endothelial progenitor cells and regeneration-associated cells in diet-induced obese mice

Metabolic syndrome (MS), overlapping type 2 diabetes, hyperlipidemia, and/or hypertension, owing to high-fat diet, poses risk for cardiovascular disease. A critical feature associated with such risk is the functional impairment of endothelial progenitor cells (EPCs). Dipeptidyl dipeptidase-4 inhibit...

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Veröffentlicht in:PLoS One
Hauptverfasser: Salybekov, Amankeldi A., Masuda, Haruchika, Miyazaki, Kozo, Sheng, Yin, Sato, Atsuko, Shizuno, Tomoko, Iida, Yumi, Okada, Yoshinori, Asahara, Takayuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424405/
https://ncbi.nlm.nih.gov/pubmed/30889182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205477
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