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Refinement of Highly Flexible Protein Structures using Simulation-Guided Spectroscopy

Highly flexible proteins present a special challenge for structure determination because they are multi-structured yet not disordered, so their conformational ensembles are essential for understanding function. Because spectroscopic measurements of multiple conformational populations often provide s...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Hays, Jennifer M., Kieber, Marissa K., Li, Jason Z., Han, Ji In, Columbus, Linda, Kasson, Peter M.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424112/
https://ncbi.nlm.nih.gov/pubmed/30395378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201810462
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