Application of the NZ‐1 Fab as a crystallization chaperone for PA tag‐inserted target proteins

An antibody fragment that recognizes the tertiary structure of a target protein with high affinity can be utilized as a crystallization chaperone. Difficulties in establishing conformation‐specific antibodies, however, limit the applicability of antibody fragment‐assisted crystallization. Here, we a...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Tamura, Risako, Oi, Rika, Akashi, Satoko, Kaneko, Mika K., Kato, Yukinari, Nogi, Terukazu
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2019
Subjects:
Methods and Applications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424065/
https://ncbi.nlm.nih.gov/pubmed/30666745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3580
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