Loss of the TAM Receptor Axl Ameliorates Severe Zika Virus Pathogenesis and Reduces Apoptosis in Microglia

The TAM receptor, Axl, has been implicated as a candidate entry receptor for Zika virus (ZIKV) infection but has been shown as inessential for virus infection in mice. To probe the role of Axl in murine ZIKV infection, we developed a mouse model lacking the Axl receptor and the interferon alpha/beta...

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Enregistré dans:
Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Hastings, Andrew K., Hastings, Katherine, Uraki, Ryuta, Hwang, Jesse, Gaitsch, Hallie, Dhaliwal, Khushwant, Williamson, Eric, Fikrig, Erol
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424058/
https://ncbi.nlm.nih.gov/pubmed/30884311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.03.003
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