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Identifying and exploiting gene-pathway interactions from RNA-seq data for binary phenotype

BACKGROUND: RNA sequencing (RNA-seq) technology has identified multiple differentially expressed (DE) genes associated to complex disease, however, these genes only explain a modest part of variance. Omnigenic model assumes that disease may be driven by genes with indirect relevance to disease and b...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genet
Main Authors: Shao, Fang, Wang, Yaqi, Zhao, Yang, Yang, Sheng
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423879/
https://ncbi.nlm.nih.gov/pubmed/30890140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-019-0739-7
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