Comparing efficacy and safety between Naldebain(®) and intravenous patient-controlled analgesia with fentanyl for pain management post-laparotomy: study protocol for a randomized controlled, non-inferior trial

BACKGROUND: A long-acting prodrug of nalbuphine, nalbuphine sebacate, has been developed for meeting the unmet medical need of long-acting analgesics. Naldebain(®) (nalbuphine sebacate) has been developed as a new premedication for postoperative pain management. The primary objective of this study i...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Tsai, Hsiang-Lin, Chang, Tsung-Kun, Su, Wei-Chih, Yeh, Yung-Sung, Huang, Ching-Wen, Ma, Cheng-Jen, Wang, Jaw-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423831/
https://ncbi.nlm.nih.gov/pubmed/30885242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3260-4
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