Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature

BACKGROUND: Primary mesenchymal stem cells (MSCs) are fraught with aging-related shortfalls. Human-induced pluripotent stem cell (iPSC)-derived MSCs (iMSCs) have been shown to be a useful clinically relevant source of MSCs that circumvent these aging-associated drawbacks. To date, the extent of the...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Spitzhorn, Lucas-Sebastian, Megges, Matthias, Wruck, Wasco, Rahman, Md Shaifur, Otte, Jörg, Degistirici, Özer, Meisel, Roland, Sorg, Rüdiger Volker, Oreffo, Richard O. C., Adjaye, James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423778/
https://ncbi.nlm.nih.gov/pubmed/30885246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1209-x
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