Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer

BACKGROUND: Oxaliplatin resistance is a major challenge for treatment of advanced colorectal cancer (CRC). Both acquisition of epithelial-mesenchymal transition (EMT) and suppressed drug accumulation in cancer cells contributes to development of oxaliplatin resistance. Aberrant expression of small n...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Liu, Tong, Zhang, Xin, Du, Lutao, Wang, Yunshan, Liu, Xiaoming, Tian, Hui, Wang, Lili, Li, Peilong, Zhao, Yinghui, Duan, Weili, Xie, Yujiao, Sun, Zhaowei, Wang, Chuanxin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423768/
https://ncbi.nlm.nih.gov/pubmed/30890168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-0981-7
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