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CK2-mediated CCDC106 phosphorylation is required for p53 degradation in cancer progression
BACKGROUND: Dysfunction of p53 is a key cause of cancer development, while CCDC106 can reduce p53 stability and is associated with lung cancer. However, the roles of CCDC106 in other cancer types and its upstream regulators have not been investigated. METHODS: The phosphorylation status was investig...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423756/ https://ncbi.nlm.nih.gov/pubmed/30885251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1137-8 |
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