MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway

BACKGROUND: Mitogen-activated protein kinase phosphatases-4 (MKP-4) is reported to exert a prognostic merit in hepatocarcinogenesis. However, the underlying molecular mechanisms have not been clearly defined. METHODS: Immunoprecipitation-mass spectrometry (IP-MS) approach was used to identify intera...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Shen, Zhongyi, Zhang, Chengliang, Qu, Lishuai, Lu, Cuihua, Xiao, Mingbing, Ni, Runzhou, Liu, Jinxia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423746/
https://ncbi.nlm.nih.gov/pubmed/30923463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0776-3
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