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Morusinol Exhibits Selective and Potent Antitumor Activity Against Human Liver Carcinoma by Inducing Autophagy, G2/M Cell Cycle Arrest, Inhibition of Cell Invasion and Migration, and Targeting of Ras/MEK/ERK Pathway

BACKGROUND: Liver cancer is one of the most commonly diagnosed cancers across the globe. The treatment is often difficult as it is diagnosed mostly at advanced stages. Moreover, the lack efficacious and less toxic drugs are another problem in the treatment of liver cancer. Against this background, i...

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Опубликовано в: :Med Sci Monit
Главные авторы: Zhu, Zhen, Xiao, Tianyu, Chang, Xuejiao, Hua, Yanfei, Gao, Jinli
Формат: Artigo
Язык:Inglês
Опубликовано: International Scientific Literature, Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423732/
https://ncbi.nlm.nih.gov/pubmed/30860205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.912992
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