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Crystal structure and calcium‐induced conformational changes of diacylglycerol kinase α EF‐hand domains
Diacylglycerol kinases (DGKs) are multi‐domain lipid kinases that phosphorylate diacylglycerol into phosphatidic acid, modulating the levels of these key signaling lipids. Recently, increasing attention has been paid to DGKα isozyme as a potential target for cancer immunotherapy. We have previously...
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| Publicado en: | Protein Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423725/ https://ncbi.nlm.nih.gov/pubmed/30653270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3572 |
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