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Nitric oxide-donor/PARP-inhibitor combination: A new approach for sensitization to ionizing radiation
Recently, clinical development of PARP inhibitors (PARPi) expanded from using them as a single agent to combining them with DNA-damaging therapy to derive additional therapeutic benefit from stimulated DNA damage. Furthermore, inhibiting PARP in cancers with BRCA1/2 mutations has been shown to be an...
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| Publicat a: | Redox Biol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423503/ https://ncbi.nlm.nih.gov/pubmed/30889466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101169 |
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