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Induction of Apoptosis by a Combination of 2-Deoxyglucose and Metformin in Esophageal Squamous Cell Carcinoma by Targeting Cancer Cell Metabolism

BACKGROUND: Both mitochondrial dysfunction and aerobic glycolysis are signs of growing aggressive cancer. If altered metabolism of cancer cell is intended, using the glycolysis inhibitor (2-deoxyglucose (2DG)) would be a viable therapeutic method. The AMP-activated protein kinase (AMPK), as a metabo...

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書目詳細資料
發表在:Iran J Med Sci
Main Authors: Shafaee, Abbas, Pirayesh Islamian, Jalil, Zarei, Davoud, Mohammadi, Mohsen, Nejati-Koshki, Kazem, Farajollahi, Alireza, Aghamiri, Seyed Mahmoud Reza, Rahmati Yamchi, Mohammad, Baradaran, Behzad, Asghari Jafarabadi, Mohammad
格式: Artigo
語言:Inglês
出版: Iranian Journal of Medical Sciences 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423430/
https://ncbi.nlm.nih.gov/pubmed/30936596
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