Development of live attenuated Enterovirus 71 vaccine strains that confer protection against lethal challenge in mice

Besides causing mild hand, foot and mouth infections, Enterovirus A71 (EV-A71) is associated with neurological complications and fatality. With concerns about rising EV-A71 virulence, there is an urgency for more effective vaccines. The live attenuated vaccine (LAV) is a more valuable vaccine as it...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Yee, Pinn Tsin Isabel, Tan, Soon Hao, Ong, Kien Chai, Tan, Kuan Onn, Wong, Kum Thong, Hassan, Sharifah Syed, Poh, Chit Laa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423319/
https://ncbi.nlm.nih.gov/pubmed/30886246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41285-z
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