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Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats

The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats. In the present study we describe that the CeA neuronal ensemble that is activated by withdrawal from chronic...

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Publicado en:Nat Commun
Autores principales: de Guglielmo, Giordano, Kallupi, Marsida, Pomrenze, Matthew B., Crawford, Elena, Simpson, Sierra, Schweitzer, Paul, Koob, George F., Messing, Robert O., George, Olivier
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423296/
https://ncbi.nlm.nih.gov/pubmed/30886240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09183-0
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