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Extension of longevity and reduction of inflammation is ovarian-dependent, but germ cell-independent in post-reproductive female mice

Cardiovascular disease, rare in premenopausal women, increases sharply at menopause and is typically accompanied by chronic inflammation. Previous work in our laboratory demonstrated that replacing senescent ovaries in post-reproductive mice with young, actively cycling ovaries restored many health...

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Détails bibliographiques
Publié dans:GeroScience
Auteurs principaux: Habermehl, Tracy L., Parkinson, Kate C., Hubbard, Gene B., Ikeno, Yuji, Engelmeyer, Jennifer I., Schumacher, Björn, Mason, Jeffrey B.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423149/
https://ncbi.nlm.nih.gov/pubmed/30547325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-018-0049-4
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