Generic synthesis of small-sized hollow mesoporous organosilica nanoparticles for oxygen-independent X-ray-activated synergistic therapy

The success of radiotherapy relies on tumor-specific delivery of radiosensitizers to attenuate hypoxia resistance. Here we report an ammonia-assisted hot water etching strategy for the generic synthesis of a library of small-sized (sub-50 nm) hollow mesoporous organosilica nanoparticles (HMONs) with...

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Publicat a:Nat Commun
Autors principals: Fan, Wenpei, Lu, Nan, Shen, Zheyu, Tang, Wei, Shen, Bo, Cui, Zhaowen, Shan, Lingling, Yang, Zhen, Wang, Zhantong, Jacobson, Orit, Zhou, Zijian, Liu, Yijing, Hu, Ping, Yang, Weijing, Song, Jibin, Zhang, Yang, Zhang, Liwen, Khashab, Niveen M., Aronova, Maria A., Lu, Guangming, Chen, Xiaoyuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423028/
https://ncbi.nlm.nih.gov/pubmed/30886142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09158-1
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