Clonal architectures predict clinical outcome in clear cell renal cell carcinoma

The genetic landscape of clear cell renal cell carcinoma (ccRCC) had been investigated extensively but its evolution patterns remained unclear. Here we analyze the clonal architectures of 473 patients from three different populations. We find that the mutational signatures vary substantially across...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Huang, Yi, Wang, Jiayin, Jia, Peilin, Li, Xiangchun, Pei, Guangsheng, Wang, Changxi, Fang, Xiaodong, Zhao, Zhongming, Cai, Zhiming, Yi, Xin, Wu, Song, Zhang, Baifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423009/
https://ncbi.nlm.nih.gov/pubmed/30886153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09241-7
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